The great depression and of mice

One of the most serious economic consequences of the Depression was mass unemployment.

The great depression and of mice

Wharton's Michael Platt and Penn's Shelley Berger discuss their interdisciplinary research on stress. Work, finances, relationships — all have the ability to create chronic stress that can lead to anxiety, depression and other issues.

Two Penn Integrates Knowledge PIK professors — Michael Platta Wharton marketing professor and professor of neuroscience and psychology at Penn, and Shelley Berger, a Penn professor of cell and development biology and director of The Epigenetics Institute, have teamed up in an interdisciplinary approach to learn more about how stress affects individuals.

Platt and Berger recently spoke about their research and its implications on the Knowledge Wharton show on SiriusXM channel Listen to the podcast at the top of this page. Following is an edited transcript of the conversation.

The great depression and of mice

Tell us the background behind this research. We actually have an ant lab at the Perelman School of Medicine. Recently, we became interested in mouse behavior and studying the brain and epigenetics in the brain.

What Ants, Mice and Monkeys Can Teach Us About the Impact of Stress - [email protected]

Through conversations with Michael, that led to how this whole thing began on crossing species and studying mouse, primate and even human. Give us a better understanding of epigenetics. Epigenetics is the study of how the environment affects the way genes are expressed.

We commonly think about mutations affecting genes and gene expression. But epigenetics is the study of how the environment can affect the way genes are turned on and off without mutation.

John Steinbeck

Post-traumatic stress disorder is a great example. Michael, tell us about your interest in this research? We have been interested in behavior for a long time. We got interested in how genes affect the development of the structure and function of the brain and nervous system to ultimately produce behavior.

Of course, that equation leaves out the central role of epigenetics that Shelley just described, which is that the same genes in the same body in a different environment can lead to very different outcomes. If you imagine yourself living with lots of family support, for example, you might respond better to the stresses of the environment — to a stock market crash, to problems in the economy, etc.

But if you are living alone without any social support, then that stressful event or the long-term stress can be much more impactful on your body and your brain.

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Shelley and I met two years ago, when I had just arrived here from Duke University…. As we were talking, we began to realize that we were interested in very similar things, although our expertise is very complementary.

We had been working on the neurophysiology of behavior, the neurophysiology of social behavior and how genetics might influence that. But we had really no expertise in epigenetics at all. How will this research lead to a better understanding of the human brain and how it reacts to stress from environmental factors?The Great Depression was a severe worldwide economic depression that took place mostly during the s, beginning in the United caninariojana.com timing of the Great Depression varied across nations; in most countries it started in and lasted until the lates.

It was the longest, deepest, and most widespread depression of the 20th . The Great Depression was a severe worldwide economic depression that took place mostly during the s, beginning in the United caninariojana.com timing of the Great Depression varied across nations; in most countries it started in and lasted until the lates.

It was the longest, deepest, and most widespread depression of the 20th century. In the 21st century, the Great Depression is. Of Mice and Men is a novel set in the United States whilst the great depression was taking place.

The story follows two protagonists, George and Lennie, who embark on a journey, which ultimately ends in tragedy. John Steinbeck’s famous hobos, George and Lennie, bring the migrant farm experience of the Great Depression to life in the celebrated classic of American literature, Of Mice and Men.

Part of the huge grain growing industry of the American west, Depression Era itinerant farm workers like George and. The Great Depression was a time of hardship for everybody especially ranch workers. It prevented people from living the life they desired. Many people lived in .

Of Mice and Men takes place during America's Great Depression, which lasted from the Stock Market Crash of October until 12 years later when World War II began.

One result of the Depression was a lack of steady jobs, which resulted in an increase in the number of itinerant workers.

Great Depression in the United States - Wikipedia